Investigation of Serum Folate-Receptor-1 Levels in Patients with Non-Small Cell Lung Cancer
نویسندگان
چکیده
Objective: Histopathological overexpression of folate receptor-1 (FOLR1) involved in transport cell growth has been reported various cancers. Increased serum FOLR1(sFOLR1) also epithelial ovarian cancer. The aim was to investigate sFOLR1 levels non-small lung cancer (NSCLC) patients and the response prediction standard chemotherapy targeting folic acid metabolism.
 Method: In this prospective study, were investigated 30 healthy individuals 60 with stage4 malign metastatic NSCLC before after chemotherapy. commercial immunoassay (ELISA) kit used for analysis sFOLR1. Serum carcinoembryonic antigen (CEA), vitamin B12, investigated. 
 Result: significantly higher(p
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ژورنال
عنوان ژورنال: Konuralp Tip Dergisi
سال: 2022
ISSN: ['1309-3878']
DOI: https://doi.org/10.18521/ktd.1165651